Fallout 4

The open world is set in USA, Massachusetts, including the Boston city. The story takes place in 2287, 10 years after Fallout 3 and 210 years after the "Great War".

You play as the "Sole Survivor" who emerges from a long-term cryogenic stasis in Vault 111, a nuclear shelter. After witnessing the murder of their spouse and the kidnapping of their son Shaun, the Sole Survivor ventures out into the Commonwealth to search for their missing child.

Compared to previous games, players can now develop and manage settlements, and there's a more advanced crafting system. It's also the first game in the series to feature a fully voiced protagonist.